@article{M1FD0748B, title = "Deep Learning-Based Approaches for Nucleus Segmentation", journal = "The Journal of Korean Institute of Communications and Information Sciences", year = "2024", issn = "1226-4717", doi = "10.7840/kics.2024.49.4.620", author = "Duy Cuong Bui, Myungsik Yoo", keywords = "Deep Learning, CNN, Nuclei Segmentation, Image Segmentation, U-Net", abstract = "The accurate identification of cell nuclei is a critical aspect of various analyses, given that human cells, numbering around 30 trillion, contain DNA as their genetic code. In this research paper, we provide a comprehensive overview of deep learning-based techniques for nucleus segmentation. We have replicated and assessed the state-of-the-art methods using datasets like FCN, SegNet, U-net, and DoubleU-net, with a focus on the Data Science Bowl 2018 dataset comprising 670 training data folders and 65 testing data folders. Our experimental findings reveal that DoubleU-Net surpasses U-Net and other baseline models, yielding more precise segmentation masks. This promising outcome suggests that DoubleU-Net could serve as a robust model for addressing various challenges in medical image segmentation." }